The objectives of THECA are:
- Typbar-TCV® Phase 3 cluster-randomized trial to measure population-level vaccine protection in Ghana
- Effectiveness evaluation of mass vaccination campaign using Typbar-TCV® in the Democratic Republic of Congo
- Generate data on mass-campaign feasibility, cost-effectiveness, safety, immunogenicity and impact on antimicrobial resistance
- Enhance capacity building for conducting clinical trials in Africa
- Support regulatory affairs for TCV introduction in Ghana, Democratic Republic of Congo, Madagascar, and Burkina-Faso