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You are here: Home / About THECA

About THECA

THECA Programme

THECA Project team in Ghana

THECA programme is to:

  • Conduct a Typbar-TCV® Phase 3 cluster-randomized trial to measure population-level vaccine protection in Ghana
  • Conduct a Typbar-TCV® mass-vaccination campaign with a nested case-control study to measure vaccine protection under realistic public health conditions in the Democratic Republic of Congo
  • Generate data on mass-campaign feasibility, cost-effectiveness, safety, immunogenicity and impact on antimicrobial resistance
  • Enhance capacity building for conducting the clinical trials in Africa
  • Support regulatory affairs for TCV introduction in Ghana, Democratic Republic of Congo, Madagascar, and Burkina-Faso

Goals

THECA Programme will fill a large gap in ongoing large-scale typhoid control efforts

Commitment

Generate critical data to enable African and international policymakers to make informed decisions on TCV introductions

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